ViviGen® and ViviGen Formable®

Cellular Bone Matrix

ViviGen represents a paradigm shift in the field of bone repair and tissue engineering by focusing on lineage committed bone cells. At every step of ViviGen’s processing, LifeNet Health has focused on maintaining the highest level of bone cell viability. ViviGen is a 361 Human Cells, Tissues, and Cellular and Tissue-based Product (HCT/P) comprised of cryopreserved corticocancellous bone containing endogenous lineage committed bone cells combined with demineralized bone delivering all three properties necessary for bone formation.

Osteogenic - Contains viable, lineage committed bone cells that are able to proliferate in vitro post cryopreservation and thaw1
Osteoconductive - Contains corticocancellous chips that provide a natural scaffold for cell attachment, cell migration, and cell proliferation1
Osteoinductive - Demineralization of the cortical bone exposes the natural growth factors within the matrix1
Safety - Every lot is aseptically processed and all final product is tested for sterility using USP<71> standards
Packaging - The rapid heat transfer not only allows for all sizes to thaw in less than 5 minutes, but is also vital for cell viability
Processing Time - ViviGen reaches cryopreservation within 72 hours, 24 hours sooner than competitive products, to maximize cell viability
Maximized Cell Viability - The processing of ViviGen is focused on protecting viable, lineage committed bone cells from recovery to implantation
Multiple Forms - ViviGen and ViviGen Formable provide a comprehensive solution to meet surgeons’ clinical needs